ZTX™ ONCOLEADS reduce time for drug discovery with in-vivo data from CDX models

CDX in-vivo cancer model in zebrafish

Choose from over 4000 human cell lines from ATCC’s extensive library or from the cell lines already characterized in our ZTX™ ONCOLEADS model.
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Reconstitute a patient-specific tumor microenvironment with immune and stroma cells

Gain new in-vivo insights into the mechanism of action of your drug through co-implantation of human tumor cells with non-malignant tumor-infiltrating cells to recapitulate the pathological communication between different cell types in the tumor microenvironment.

Well-characterized Cell Derived Xenograft (CDX) models are used to test anti-tumor and anti-metastatic efficacy in a relevant and controllable microenvironment that mimics the microenvironment of the tumor.

Screen many CDX models to find a new indication for your drug

Test a variety of cell lines derived from tumors from different anatomical locations to screen alternative indications to achieve the highest therapeutic potential.

Using well-characterized clonal cultures of tumor cell lines maximizes experimental control and accuracy of data interpretation. We have broad experience with using different CDX models for different diagnoses. 

Test combinations of lead candidates with a variety of other treatments

Find the best treatments to combine with your drug candidate by screening a large number of combinations in multiple CDX models, with or without the addition of non-malignant tumor-infiltrating cells.

Explore how to use your different molecules in the ZTX™ platform

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