Ztxtm-oncoleads models created from pdx-material closely recapitulate patients’ cancer and provide accurate insights into both anti-tumor and anti-metastatic drug efficacy.

Patient-derived xenograft (PDX) models in zebrafish larvae provides a unique humanized oncology drug discovery platform that mimics the complex tumor environment and pathophysiology of the patient. These models therefore increase the accuracy and translatability of the results and thereby reduce the risk of selecting non-viable lead drug candidates for further analysis.

List of PDX-models

ZTX™ -Oncoleads is a powerful tool for evaluating PDX-models for drug efficacy.

Small molecules zebrafish
Choose between hundreds of extensively characterized pdx models in our partner charles river laboratories’s vast library

Screen anti-tumor efficacy for your next mouse PDX study

Metastasis in zebrafish

Assess the inter-patient variability in drug efficacy and identify responding patient sub-groups using PDX-models

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation.

Create your PDX clinical trial in late pre-clinical development of anti-cancer drugs

Metastasis in zebrafish

Design customized PDX trials together with Charles River Laboratory upon request or join BioReperia-hosted PDX-trials.

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis.

Use ZTX™ - Oncoleads

Metastasis in zebrafish

Predict anti-metastatic responses to commonly used anti-cancer drugs

Explore how to use your different molecules in the ZTX-platform

envelope-ofacebooklinkedin