A unique ZTX®platform
BioReperia´s ZTX®platform provides in-vivo data on tumor regression and metastasis inhibition of compounds.
Highly translational model with superior diagnostic accuracy for all stages of drug development and clinical evaluation
We care about patients
Early stage
At this early stage, the embryo´s immune system is not yet developed, which allows human cells to grow within the embryo without risk of rejection.
Do not require ethical permissions
At these stages, zebrafish embryos are not considered research animals and do not require ethical permissions for the experiments.
Clear view
At these stages of development, the embryo is transparent, allowing a clear view in the microscope of the growing fluorescent-labeled human cancer cells.
Fast development
The fast development of the embryo enables rapid vascularization of the developed microtumor, allowing cells to disseminate from the primary tumor site to the vasculature and to the surrounding tissues.
Vascularized tumor
The solid tumor is vascularized within 3 days and allows metastasis invasion, which makes this an excellent tool for screening tumor regression and metastasis invasion.
Immune oncology applications
A human immune system can be reconstituted without prior immune suppression allowing for reliable evaluation of immunotherapies.
Watch our video about how our
ZTX® model can assist in your drug development
The way a zebrafish can aid in oncology drug development!